Dietary Supplements For Treatment of Arthritis From the Cleveland Clinic

WebMD Medical Reference provided in collaboration with The Cleveland Clinic

Many people with arthritis -- especially osteoarthritis -- use supplements to ease the pain of arthritis. Glucosamine and chondroitin are the most well known and best tested. Methyl sulfonylmethane, or MSM, is another supplement used to ease the pain of arthritis, but it has not been through as much rigorous scientific testing.

What Are Glucosamine and Chondroitin?

Glucosamine and chondroitin sulfate are components of normal cartilage. In the body, they are the building blocks for cartilage and appear to stimulate the body to make more cartilage.
There are conflicting studies on glucosamine and chondroitin, some demonstrating a beneficial effect on osteoarthritis pain. Others, including the NIH-sponsored multicenter

Glucosamine/Chrondroitin Arthritis Intervention Trial (GAIT), did not show benefit for the primary outcome measure of osteoarthritis pain measured by WOMAC (Western Ontario and McMacster Universities). However, a smaller subgroup of study participants with moderate to severe pain did show significant relief. Due to the small size of this subgroup, these findings should be confirmed in larger studies.

The supplements, which are available in pharmacies and health food stores without a prescription, are well tolerated and appear to be safe. However, there are no long-term studies to confirm their long-term safety and effectiveness. Many physicians may still recommend a trial of glucosamine at this point, and if there is not apparent improvement by 3 months, it would reasonable to stop the treatment.

It is important to check with your doctor before starting any new treatments. Your doctor can review the other medications you are taking and help you decide whether or not these arthritis supplements are right for you. In addition, always follow the instructions on the medication label. Do not take more of the supplements than is recommended. Continue Reading ...

All About Osteoarthritis and Women

By Jeanie Lerche Davis

WebMD Feature

Reviewed By Charlotte Mathis, MD

If you've just been diagnosed with osteoarthritisosteoarthritis (OA), you're not alone. Many women past age 50 discover OA is the reason for their creaking knees, aching backs, and sore fingers. Suddenly life is all about osteoarthritis -- but luckily, arthritisarthritis doesn't have to take control.

Arthritis is "the most common form of disability. It's also a natural part of aging," says Primal Kaur, MD, director of the Osteoporosis Clinic at Temple University School of Medicine in Philadelphia.

In the U.S., one in five adults has osteoarthritis -- 24 million women and 17 million men, according to the Arthritis Foundation. Continue Reading ...

Just Plane Stiff

by Linda J. Brown

Posted 2/17/07

Stiff, achy joints and muscles can be felt by anyone who sits through a long airline flight, but especially by those who have arthritis.

"You have to keep moving to keep your joints from getting stiff and painful," says Marilyn Moffat, PhD, professor of physical therapy at New York University. Moffat, who advises walking the aisles as much as possible during flights, developed the following simple moves, each repeated five to 10 times, for the American Physical Therapy Association.

Heel raises. Sit with feet flat on the floor, hip-width apart. Lift heels off floor, hold for five to 10 seconds and lower heels to the ground.

Ankle circles. While sitting, lift right leg slightly off the ground and circle your foot clockwise. Circle 15 times clockwise and 15 times counterclockwise. Repeat with the left foot.

continue reading ...

Omega-3s Revealed

Researchers have long known omega-3 fatty acids help reduce inflammation. Now they know how.

by Linda RichardsPosted 2/12/07

Understanding how your body benefits from eating omega-3 fatty acids is an important part of understanding why you should eat them. But, until recently, no one really knew what made omega-3s so beneficial. Researchers, however, have uncovered the secret of omega-3 fatty acids. A study at Brigham and Women’s Hospital in Boston revealed that omega-3s actually convert into compounds that are 10,000 times more potent than the original fatty acids themselves. So what does this mean to us? The new compounds include resolvins, which help bring the inflammatory response to an end, says the study’s lead researcher, Charles Serhan, PhD, director, Center for Experimental Therapeutics and Reperfusion Injury at Harvard Medical School, Boston. Continue reading ...

New Drug for Arthritis?

New drug for arthritis?: Merck seeking FDA approval for Arcoxia, a chemical relative of Vioxx, which was linked to heart attacks

Kathleen Kerr, Newsday, Melville, N.Y.

Mar. 21, 2007 -- In a bid to recapture a piece of the arthritis pain-relief market, Merck & Co. is seeking government approval for Arcoxia, a chemical relative of Vioxx, the drug pulled off drugstore shelves in 2004 after being linked to heart attacks.

In its last full year on the market, Vioxx brought in about $2.5billion in sales. If the Food and Drug Administration approves Arcoxia, Merck could recoup some of those sales.

On April 12 an FDA advisory panel will consider approval of Arcoxia for osteoarthritis; it is already sold in 62 other countries. The FDA usually follows advisory panel recommendations. Continue reading ...

Reminder - Next Arthritis support group meeting is March 2nd, Friday ...

The Arthritis Support Group of South Lake County will meet Friday, March 2, Friday from 12 noon till to 1:30 pm. The Arthritis Support Group meeting takes place at the National Training Center / Education Department, 1109 Citrus Tower Blvd., Clermont.

All afflicted by Arthritis (there are more than 100+ types!), family, friends and those interested are welcome. Fee: Free. Brochures and literature is available at the meeting.

Guest Speaker will be Jennifer from the Clermont Herb Shop and Day Spa located in Historic Downtown Clermont. The topic and presentation will be about “Aromatherapy.” For more information, please call Meg King at (352) 243-2098.

Arthritis Support Group Meeting Reminder

The Arthritis Support Group of South Lake County will meet February 2nd, Friday, at the National Training Center / Education Department, 1109 Citrus Tower Blvd., Clermont. The meeting will start at 12PM - 1:30 PM.

The Topic will be “Exercise and Nutrition Can Help Relieve the Pain and Inflammation Caused by Arthritis.” Put your sneakers on and bring a snack to share. We are going to have some fun!

Those that have Arthritis or those that are not sure, family, friends and anyone interested in Arthritis are welcome to attend the support group. Fee: Free. Brochures, literature and books are available at the meeting.

The Arthritis Support Group of South Lake County meets the 1st Friday of each month at the NTC. For more information, please call Meg King at (352) 243-2098.

On / Off Switch for Pain Discovered

(Ivanhoe Newswire) -- Those who suffer from chronic pain have a choice: let your life be disrupted by constant pain or take pain medications that can also disrupt your life. Now new research reveals there is a new way to turn off the pain.

Chronic pain often begins with an injury or illness. Initially, the damaged nerves send pain signals to the brain. Once the damage has healed, the pain signals stop ... unless a kind of pain switch gets stuck in the on position. Until now, scientists did not know what that switch was.

Researchers from Columbia University Medical Center in New York discovered that the pain switch is a protein called protein kinase G (PKG). Their next goal is to discover the best way to block PKG and turn off the pain.

About 48 million Americans suffer from chronic pain.

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/.

SOURCE: Neuroscience, published online August 2006